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  • The rate of E-to-A conversion and the proportions of the completely different A forms synthesized in vitro had been just like these noticed for the tissues in vivo at comparable times.
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The price of E-to-A conversion and the proportions of the completely different A varieties synthesized in vitro have been much like those noticed for the tissues in vivo at comparable occasions. These results suggest that the publish translational processing in vitro was similar to that in vivo. The data have been consistent with the likelihood that the increase in synthesis of A forms occurred both in cells that had previously synthesized E types or in a definite population of cells that already synthesized A forms. In pulse-chase experiments, the E form of N-CAM that was synthesized in the course of the first day after explantation persisted as E kind for several days, at occasions when newly synthesized N-CAM was predominantly in A varieties.

Data that is obtainable includes informati… The neural cell adhesion molecule (N-CAM) inhibits proliferation in primary cultures of rat astrocytes. The mechanism of binding of neural cell adhesion molecules.